Arginine-dependent gene regulation in Streptococcus gordonii arcR regulator knockout. Streptococcus gordonii str. Challis

We have previously shown that responses of the oral bacterium Streptococcus gordonii to arginine are co-ordinated by three paralogous regulators: ArcR, ArgR and AhrC. This set of experiments was designed to assess the effects of the ArcR gene regulator on global gene expression in Streptococcus gordonii under high arginine or following a shift to no arginine. Overall design: Single colour microarrays were used to measure gene expression in four biological replicates of S. gordonii cells cultured, with and without arginine restriction.