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HUMAN PI3KDELTA IN COMPLEX WITH LASW1579

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5m6u
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HUMAN PI3KDELTA IN COMPLEX WITH LASW1579 Descriptor: 4-azanyl-6-[[(1~{S})-1-(4-oxidanylidene-3-phenyl-pyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Authors: Segarra, V, Hernandez, B, Lozoya, E, Blaesse, M, Hoeppner, S, Jestel, A. Deposit date: 2016-10-26 Release date: 2017-02-01 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Discovery of a Potent, Selective, and Orally Available PI3K delta Inhibitor for the Treatment of Inflammatory Diseases. ACS Med Chem Lett, 8, 2017
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2016-10-26
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