Structure of DDB1 bound to CR8-engaged CDK12-cyclinK
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Structure of DDB1 bound to CR8-engaged CDK12-cyclinK Descriptor: (2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-ol, Cyclin-K, Cyclin-dependent kinase 12, ... Authors: Bunker, R.D, Petzold, G, Kozicka, Z, Thoma, N.H. Deposit date: 2019-11-07 Release date: 2020-06-17 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3.46 Å) Cite: The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K. Nature, 585, 2020
创建时间：
2019-11-07
