Human stool Raw sequence reads. Human stool

Parkinson’s disease (PD) is one of the most common neurodegenerative disorders. It has been repeatedly reported that most patients with PD suffer from gastrointestinal dysfunctions and alterations of the autonomous nervous system in the gut wall called the enteric nervous system (ENS). Such alterations and functional gastrointestinal deficits might occur years before the classical clinical symptoms of PD appear. Until now, only little is known about PD-associated changes in gut microbiota composition and their implication in PD development. Due to variance in previously published reports about the differences between community composition in PD and non-PD patients, our intention is to increase knowledge in this field with the use of two next generation sequencing (NGS) methods (Illumina MiSeq and Ion Torrent PGM) on the same set of samples.