Treatment outcomes by WT-<i>IRF8</i> expression.

OR = odds ratio; HR = hazard ratio; Events = relapses from CR or death from any cause; CI = confidence interval. P = two-sided p-value from logistic regression (CR, RD) or proportional hazards regression (OS, RFS), treating WT-IRF8 expression as a dichotomous variable (“Two groups”, i.e., >2-fold vs. ≤2-fold) or as a continuous variable (“Trend”). “Adjusted” analyses include the following covariates, which were identified as significant in multivariate analyses: CR: age, CD34 expression (fold-change), and performance status (2–3 vs. 0–1); RD: age, CD34 expression, and FLT3-ITD (present vs. absent); OS: age, CD34 expression, and performance status; RFS: age.