Deciphering a functional gene network underlying robustness to protein overproduction

We systematically investigated the impact of genetic variation and the environment on protein overproduction costs in Saccharomyces cerevisiae To identify genes mediating protein overproduction costs, genetic perturbations were applied本研究系统性地探究了遗传变异与环境对酿酒酵母（Saccharomyces cerevisiae）蛋白质过量生产成本的影响。为了鉴定介导蛋白质过量生产成本的基因，我们施加了遗传扰动。