Ten molecular signatures from genomics data used for predicting novel RLR pathway components.

a Data used directly (d) or as basis for further calculation (c)b Combination of all bins with positive likelihood ratio scores per feature, derived from Fig 1Ac RLR genes versus non-RLR genes: P(Di | RLR genes) / P(Di | non-RLR genes), see Methods.Note that, to avoid circularity, the predictive ability of the co-expression, protein domain and RLR pathway PPI data sets was assessed using the set of TLR, CLR, NLR, cytDNA genes instead of the RLR genes (see Methods).See also Fig 1A and S1 Table.Ten molecular signatures from genomics data used for predicting novel RLR pathway components.