Immune Responses and Hypercoagulation in ERT for Pompe Disease Are Mutation and rhGAA Dose Dependent - Figure 1

A) Experimental timeline B) Core temperature measurements prior to and post the 8th rhGAA IV injection in wt 129 SVE and wt BALB/c mice (n = 5) C) Anti-rhGAA IgG1 antibody in 129SVE wt mice D) Anti-rhGAA IgG1 antibody in BALB/c mice E) Anti-rhGAA IgG2a antibody in wt 129SVE mice F) Anti-rhGAA IgG2a antibody in wt BALB/c mice.