ALK in complex with NVL-655 with in-silico mutated residue
收藏Figshare2025-01-22 更新2026-04-08 收录
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https://figshare.com/articles/dataset/ALK_in_complex_with_NVL-655_with_in-silico_mutated_residue/28220165/1
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资源简介：
PyMol session file (.pse) files of the structure of ALK in complex with NVL-655 (original PDB accession 9GBE) with <i>in-silico</i> mutated residues as reported in figure 4. Computational mutagenesis was applied to residues known to confer resistance to TKIs in order to highlight their potential impact on drug binding and efficacy. The mutated residues are represented simultaneously for illustrative purposes.
提供机构：
Iannelli, Fabio
创建时间：
2025-01-22
