Edn1

ENCODES a protein that exhibits endothelin A receptor binding; endothelin B receptor binding; cytokine activity (ortholog); INVOLVED IN artery smooth muscle contraction; cellular response to calcium ion; cellular response to fatty acid; PARTICIPATES IN inflammatory response pathway; endothelin signaling pathway; hypoxia inducible factor pathway; ASSOCIATED WITH adult respiratory distress syndrome; Albuminuria; aspiration pneumonia; FOUND IN basal part of cell; extracellular space; rough endoplasmic reticulum lumen; INTERACTS WITH (+)-catechin; (R)-noradrenaline; 1,3-dinitrobenzene

编码一种蛋白质，该蛋白质具有内皮素A受体结合能力、内皮素B受体结合能力以及细胞因子活性（同源物）；参与动脉平滑肌收缩、细胞对钙离子的反应以及细胞对脂肪酸的反应；参与炎症反应途径、内皮素信号通路和缺氧诱导因子通路；与成人呼吸窘迫综合征、蛋白尿、吸入性肺炎相关；存在于细胞基底部、细胞外空间、粗面内质网腔内；与（+）儿茶素、（R）-去甲肾上腺素和1,3-二硝基苯相互作用。