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Honokiol Bis-Dichloroacetate (Honokiol DCA) Demonstrates Activity in Vemurafenib-Resistant Melanoma in Vivo.

ChEBI2016-01-20 更新2026-07-12 收录

黑色素瘤耐药性

临床前药效评估

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-76956 数据链接链接失效反馈

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Honokiol Bis-Dichloroacetate (Honokiol DCA) Demonstrates Activity in Vemurafenib-Resistant Melanoma in Vivo.

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创建时间：

2016-01-20

药物组合筛选

临床前药效评估

Drug combinations are becoming a standard treatment of many complex diseases due to their capability to overcome resistance to monotherapy. In the current preclinical drug combination screening, the t

NIAID Data Ecosystem90

Proteomics identifies markers of MAPKi resistance offering new therapeutic strategies in melanoma- Cytoplasmic (cyt), nuclear (ne) and secreted (sn) proteins of MAPKi sensitive melanoma cells

黑色素瘤耐药性

蛋白质组学生物标志物

MAPK inhibitors (MAPKi) show outstanding clinical response rates in melanoma patients harbouring BRAF mutations, but resistance is common. High-throughput, subcellular proteome analyses at two differe

NIAID Data Ecosystem60

Combination treatment with 17-AAG and CDDP or DTIC.

肿瘤联合用药

临床前药效评估

Combination treatment with 17-AAG and CDDP or DTIC.

Figshare2016-04-06 更新40

Gene expression profiling of oncogenic NRAS driven mouse melanomas that have developed resistance to NRAS withdrawal. Mus musculus

黑色素瘤耐药性

RAS突变肿瘤

Targeted therapies have the potential to revolutionize cancer care by providing personalized treatment strategies that are less toxic and more effective but it is clear that for most solid tumors supp

NIAID Data Ecosystem70

Acetylcytidine modification of DDX41 and ZNF746 by N-acetyltransferase 10 contributes to chemoresistance of melanoma

黑色素瘤耐药性

RNA修饰机制

We performed RNA-seq to analyse the different expression genes of DTIC-resistant (DR) A375 cells and wild-type control. Examination of differentially expressed genes in DR A375 cells compared with wil

NIAID Data Ecosystem50

Honokiol Bis-Dichloroacetate (Honokiol DCA) Demonstrates Activity in Vemurafenib-Resistant Melanoma in Vivo.

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