five

Supporting data for The Functional Roles of SCD1/FADS2 Lipid Desaturases in Modulating Lipid Metabolic Activities and Redox-driven Ferroptosis in Ascites-derived Ovarian Cancer Cells

收藏
DataCite Commons2021-08-17 更新2025-04-16 收录
下载链接:
https://datahub.hku.hk/articles/dataset/Supporting_data_for_The_Functional_Roles_of_SCD1_FADS2_Lipid_Desaturases_in_Modulating_Lipid_Metabolic_Activities_and_Redox-driven_Ferroptosis_in_Ascites-derived_Ovarian_Cancer_Cells/15134379/1
下载链接
链接失效反馈
官方服务:
资源简介:
1. The desaturation abilities of SCD1/FADS2 are aberrantly augmented in ascites-derived ovarian cancer cells.2. SCD1/FADS2 causes the elevation of poly- and mono-unsaturated fatty acids (UFAs) and enhanced oncogenic properties of ovarian cancer cells.3. SCD1/FADS2 modulates GSH/GSSG ratio and GPX4, preventing induction of ferroptosis.4.Targeting suppression of SCD1/FADS2 synergistically enhances cisplatin-mediated cytotoxicity in ascites-derived ovarian cancer cells.
提供机构:
University of Hong Kong
创建时间:
2021-08-17
二维码
社区交流群
二维码
科研交流群
商业服务