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Effect of meiosis specific cohesin subunit SMC1 on chromatin architecture in primary murine spermatocytes [RNA-Seq 2]

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NIAID Data Ecosystem2026-05-01 收录
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To investigate the function of meiosis-specific SMC1beta on chromatin architecture near the telomeric end in primary murine spermatocytes we used a SMC1beta knockout mouse model. Overall design: Further to study seperation of function of universal cohesin subunit SMC1alpha and meiosis specific SMC1beta, we compared open chromatin between SMC1b knockout spermatocytes and SMC1alpha overexpressed in a SMC1beta knockout mouse model.

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2023-05-05
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