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Crystal structure of the first bromodomain of human BRD4 in complex with bromosporine (BSP)

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Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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Crystal structure of the first bromodomain of human BRD4 in complex with bromosporine (BSP) Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, Bromosporine Authors: Filippakopoulos, P, Picaud, S, Felletar, I, von Delft, F, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2016-02-28 Release date: 2016-10-19 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia. Sci Adv, 2, 2016
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2016-02-28
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