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RNA-Seq analysis of Pold3 inducible-knockout embryonic stem cells

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE100945
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To investigate the molecular changes and mechanism during loss of Pold3, Pold3 induble-knockout embryonic stem cells at different passages were subjected to RNA-seq analysis. We found that aberrant cell cycle and defective DNA repair were induced by loss of Pold3. Detection of changes in transcriptome levels at diffrerent passages (P0, P1 and P2)
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2020-07-07
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