Green derivative synchronous spectrofluorimetry for kinetic stability study of florfenicol

This dataset contains data representing synchronous fluorescence spectra obtained upon utilizing spectrofluorometry as a highly sensitive analysis tool for the simultaneous determination of Florfenicol with its different degradation products obtained after stress testing. Synchronous fluorimetry was used followed by applying either first or second derivatization according to the type of degradation aiming to obtain highly resoluted spectra. Different degradation pathways according to published literature were used to interpret degradation kinetic parameters, which were in accordance with previously reported articles. The dataset also includes different validation parameters applied.

Methods
The dataset was collected during the measurement of fluorescence following the acidic, alkaline, oxidative, and photolytic degradation of FLR at different temperature settings at predetermined time intervals. Labsolution software was used to apply synchronous fluorimetry at different Δλ, followed by either first or second derivatization. The experiments were carried out in the Central Laboratory at the Faculty of Pharmacy Delta University for Science and Technology. The synchronous fluorescence spectra illustrated in the following table are the result of measuring the synchronous fluorescence relative intensity on the Y axis versus the emission wavelength on the X axis.