Nominal P Values of Identified Candidate Genes Exhibiting Excesses of Rare Variants.

NA, not assessed.*Significant after Bonferoni Multiple testing.aSignificant excess of missense and rare missense variants versus silent variants, compared to the rest of genes pooled together in each cohort and separately for X chromosome and autosomes.bSignificant excess of individuals with rare missense variants in a given gene. QNTS controls used for the ASD cohort and schizophrenia negative controls used for the schizophrenia cohort.cSignificant impact on the overall (autosomes) site frequency spectrum within each disease cohort.dMean γmkprf of disease cohort and control in parentheses.**denote mean γ significantly more negative in the disease cohort than among QNTS (ASD), SN (SCZ), or Western-European controls. NA are for genes with no available divergence data.