The Loeys-Dietz syndrome (LDS) is an inherited connective tissue disorder caused by mutations in the transforming growth factor β (TGF-β) receptors TGFBR1 or TGFBR2. Most patients with LDS develop sev
Data are presented as median [IQR] for lag time, normalized ETP (nETP), normalized peak height (nPeak Height) and the reduction on ETP upon addition of thrombomodulin (reduced ETP). Thrombin generatio
The Loeys-Dietz syndrome (LDS) is an inherited connective tissue disorder caused by mutations in the transforming growth factor β (TGF-β) receptors TGFBR1 or TGFBR2. Most patients with LDS develop sev
Data are presented as median [IQR] for lag time, normalized ETP (nETP), normalized peak height (nPeak Height) and the reduction on ETP upon addition of thrombomodulin (reduced ETP). Thrombin generatio