Decreased life span in single-gene deletion strains from the binding shortest-path longevity network relative to randomly selected strains.

The percentage of single-gene deletion strains with an observed mean replicative life span (MRLS) less than 20 or 15 in the Binding shortest-path longevity network (SPLN), a randomly selected set of 564 deletion strains (R564), or the 4681 deletion strains from the deletion collection for which RLS data has been obtained (DELSET) is shown. The number of strains in each category is shown in parentheses. The p-value category refers to the results of a Fisher's Exact test comparing the frequency of short RLS in each random set (R564 or DELSET) relative to the Binding SPLN.