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Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells

ChEBI2015-04-01 更新2026-07-21 收录

细胞分化机制

浆细胞转录组学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-60927 数据链接链接失效反馈

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资源简介：

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells

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创建时间：

2015-04-01

细胞分化机制

抗体亲和力成熟

Long-lived plasma cells (PCs) secrete antibodies that can provide sustained immunity against infection. It has been proposed that high affinity cells are preferentially selected into this compartment,

NIAID Data Ecosystem60

Effect of recombinant Shh on gene expression of primary rat nucleus pulposus cells

浆细胞转录组学

Shh信号通路抑制

In order to study the effect of recombinant Shh (rShh) on nucleus pulposus cells, primary nucleus pulposus cells from SD rats were obtained.Then, nucleus pulposus cells were treated with rShh at 200 n

NIAID Data Ecosystem50

Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4 (ChIP-seq)

细胞分化机制

ChIP-seq分析

Temporal analysis of Irf4 and PU.1 genome binding during B cell activation and differentiation in vitro using antigen (NP-Ficoll) CD40L and IL-2/4/5 cytokines (see Molecular Systems Biology 7:495 for

NIAID Data Ecosystem40

Tbet regulates the accessible chromatin of Be1 B cells. Tbet regulates the accessible chromatin of Be1 B cells

细胞分化机制

染色质可及性分析

To investigate the role of Tbet in B cell differentiation to "effector-like" antibody secreting cells (ASC's) we utilized an ex vivo culture system to differentiate B cells in the presence of Th1 (Be1

NIAID Data Ecosystem60

FTH1P3, a Novel H-Ferritin Pseudogene Transcriptionally Active, Is Ubiquitously Expressed and Regulated during Cell Differentiation

基因转录调控

细胞分化机制

Ferritin, the major iron storage protein, performs its essential functions in the cytoplasm, nucleus and mitochondria. The variable assembly of 24 subunits of the Heavy (H) and Light (L) type composes

NIAID Data Ecosystem40

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells

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