WP5492 - AMPK regulation of mammary milk protein synthesis - Homo sapiens
收藏NIAID Data Ecosystem2026-05-02 收录
下载链接：
https://www.ndexbio.org/viewer/networks/e412b2b3-1438-11f0-9806-005056ae3c32
下载链接
链接失效反馈官方服务：
资源简介：
"AMPK regulates mammary milk protein synthesis: mTORC1 is the master regulator that controls milk protein synthesis in the mammary gland through 4EBP1 and S6K1. AMPK directly inhibits mTORC1 through the phosphorylation of raptor at Ser 792. AMPK also decreases mTOR activity through the phosphorylation of TSC2 (a negative mTORC1 regulator) at Ser1345. The genes encoding as1-casein (CSN1S1), β-casein (CSN2) and κ-casein (CSN3) are also decreased with the activation of AMPK."
Derived from Figure 4 in https://pmc.ncbi.nlm.nih.gov/articles/PMC7332552.
创建时间：
2025-04-17
