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Capsule switching experiments 2. Streptococcus pneumoniae

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1227533
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Two pneumococcal isolates had their capsule deleted using Phun-Sweet-Janus and replaced by donor capsules using transformation with gDNA. The isolates were then characterized in growth experiments. From genomic data, the goal is to evaluate additional genes that were exchanged with the capsule, to determine the location of the breakpoints and factors associated with the length of recombination events.
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2025-02-24
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