MEK1 Kinase bound to small molecule inhibitor G659
收藏Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4u81
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资源简介：
MEK1 Kinase bound to small molecule inhibitor G659 Descriptor: 8-[(4-cyclopropyl-2-fluorophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-7-carboxamide, Dual specificity mitogen-activated protein kinase kinase 1, MAGNESIUM ION, ... Authors: Robarge, K.D, Ultsch, M.H, Weismann, C. Deposit date: 2014-07-31 Release date: 2014-09-24 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.701 Å) Cite: Structure based design of novel 6,5 heterobicyclic mitogen-activated protein kinase kinase (MEK) inhibitors leading to the discovery of imidazo[1,5-a] pyrazine G-479. Bioorg.Med.Chem.Lett., 24, 2014
创建时间：
2014-07-31
