Cohesin loss-of-function mutations are frequently observed in tumors, but the mechanism is unclear. Here, we found that depletion of RAD21, a core subunit of cohesin, leads to massive genome-wide DNA

NIAID Data Ecosystem30

Additional file 2 of Integrative modeling of multi-omics data to identify cancer drivers and infer patient-specific gene activity

癌症驱动基因

多组学整合分析

GoF and LoF gene scores for those genes that are mutated in more than 1 % of the samples. (CSV 37.9 kb)

Figshare2016-12-15 更新60

Total number of non-silent mutations in the top predicted genes by different methods trained on the TUSON database.

癌症驱动基因

基因突变分析

Total number of non-silent mutations in the top predicted genes by different methods trained on the TUSON database.

NIAID Data Ecosystem40

Mutation of cancer driver MLL2 results in transcription stress and genome instability

资源简介：

相关数据集