Crystal structure of human WDR5 in complex with compound OICR-9429
收藏Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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Crystal structure of human WDR5 in complex with compound OICR-9429 Descriptor: 1,2-ETHANEDIOL, GLYCEROL, N-(4-(4-methylpiperazin-1-yl)-3'-(morpholinomethyl)-[1,1'-biphenyl]-3-yl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide, ... Authors: Dong, A, Dombrovski, L, Walker, J.R, Getlik, M, Kuznetsova, E, Smil, D, Barsyte, D, Li, F, Poda, G, Senisterra, G, Marcellus, R, Al-Awar, R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Schapira, M, Vedadi, M, Wu, H, Structural Genomics Consortium (SGC) Deposit date: 2014-06-10 Release date: 2014-12-17 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Pharmacological targeting of the Wdr5-MLL interaction in C/EBP alpha N-terminal leukemia. Nat.Chem.Biol., 11, 2015
创建时间：
2014-06-10
