TGIF1 loss contributes to progression of KRASG12D-induced pancreatic ductal adenocarcinoma involving HAS2-CD44 activation and PD-L1 upregulation.. TGIF1 loss contributes to progression of KRASG12D-induced pancreatic ductal adenocarcinoma involving HAS2-CD44 activation and PD-L1 upregulation.
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA429336
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资源简介：
Transcriptional profiling of mouse Pancreatic cancer cells comparing Pdx1-Cre LSL-KrasG12D TGIF1L/L P53L/L cells with Pdx1-Cre LSL-KrasG12D P53L/L cells, and to determine the effects of TGIF1 deletion on PDAC gene expression. Overall design: Two-condition experiment, Pdx1-Cre LSL-KrasG12D TGIF1L/L P53L/L cells vs. Pdx1-Cre LSL-KrasG12D P53L/L cellss, 2 KrasG12D and P53L/L mutant replicates and 2 2 KrasG12D, TGIF1 and P53 mutant replicates.
创建时间：
2018-01-08
