Ventral midbrain-type neural stem/precursor cells (VM-NSCs) derived from human midbrain organoids as a stable source for treating symptoms of Parkinson’s disease
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE144062
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In this study, midbrain-like organoids were yielded from hPSCs to prepare cells suitable for PD therapy. Neural stem/precursor cells (NSCs) isolated from midbrain organoids (Og-NSCs) expanded stably and differentiated into mDA neurons, and an unprecedentedly high proportion express midbrain-specific factors. mRNA profile of 2D culture system derived NSCs, Midbrain Organoid derived NSCs
创建时间:
2020-01-23



