Effects of continuous X-ray irradiation with different peak energies and dose rates on the proliferation of C. neoformans.

As discussed in the main text, radiation effects were quantified by calculating the radiation-induced change (Qe) in CFU/ml, normalized by the initial cell concentration, as follows: Qe = (Xr(i) – Xc)/X0, where Xr(i) is the CFU/ml for each irradiated culture, Xc is the mean CFU/ml for corresponding unirradiated controls, and X0 is the mean CFU/ml at the start of irradiation. Qe represents the number of extra descendants produced by each founder cell due to the effects of irradiation on cell proliferation.