Expression data from Hes1 conditional knock-out NOTCH1-induced leukemias
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE65863
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资源简介：
To formally address the biological activity of Hes1 in vivo, we tested the interaction between oncogenic NOTCH1 and acute Hes1 loss in a retroviral-transduction bone marrow transplantation model of NOTCH-induced T-ALL Forced expression of activated NOTCH1 in this model typically results in full leukemia transformation 5-10 weeks later. We performed microarray gene expression analysis of Hes1 wild type and Hes1-/- NOTCH1 induced leukemias
创建时间：
2019-01-16
