Novel signaling roles of signalogs relevant for drug target discovery.

Predicted signaling roles of human signalog proteins that are relevant in drug target discovery. The list of drug target proteins was downloaded from DrugBank [50]. The relevance score (for being a drug target) is the number of properties out of the following 4: membrane protein, enzymes, protein has a kinase domain, and disease-relatedness (see Fig. 6 and the main text for details). The list of human signalogs and their drug target relevance scores are available in Table S2.