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Transcription profiling of mouse HSF1+/+ and HSF1-/- fibroblasts heat shock time series

ChEBI2005-07-21 更新2026-07-21 收录

热休克应激转录组

HSF1 (热休克转录因子1)

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-SMDB-1853 数据链接链接失效反馈

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资源简介：

Transcription profiling of mouse HSF1+/+ and HSF1-/- fibroblasts heat shock time series

应用场景：

创建时间：

2005-07-21

热休克信号网络

HSF1 (热休克转录因子1)

Although HSF1 is known to play an important role in regulating the cellular response to proteotoxic stressors, little is known about the structure and function of the HSF1 signaling network under both

NIAID Data Ecosystem100

Transglutaminase Type 2 regulates the Wnt/β-catenin pathway in vertebrates

Wnt/β-catenin信号通路

HSF1 (热休克转录因子1)

In this study we analyzed the effect of TG2 on the modulation of gene expression by defining its effects on the cellular mRNA profile. To address this point we analyzed, by RNA seq, the effect of TG2

NIAID Data Ecosystem90

Transcriptomic analysis of HSF1 knockout cardiomyocytes. Transcriptomic analysis of HSF1 knockout cardiomyocytes

心肌细胞转录组学

HSF1 (热休克转录因子1)

Transcriptomic analysis revealed differences in gene expression between control and HSF1 knockout cells, revealing how HSF1 gene regulation may be altered when knocked out. Overall design: We performe

NIAID Data Ecosystem50

Heat Shock Transcription Factor 1 Specifically Regulates AML Stem Cell Self-Renewal

AML（急性髓系白血病）

HSF1 (热休克转录因子1)

Acute myeloid leukemia (AML) is maintained by a small minority of self-renewing leukemic stem cells (LSCs). Defining and targeting key molecules specifically regulating LSCs hold promise for eradicati

NIAID Data Ecosystem100

BCL6 evolved in vertebrates as a stress tolerance gene and is broadly used by cancer cells to adapt to stress

热休克应激转录组

BCL6转录抑制功能

We have found that BCL6 is a component of the conserved stress response program regulated by HSF1. BCL6 mediates cellular adaptation to stress by repressing genes through its BTB domain. These genes f

NIAID Data Ecosystem60

Transcription profiling of mouse HSF1+/+ and HSF1-/- fibroblasts heat shock time series

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