Sgk1

ENCODES a protein that exhibits 3-phosphoinositide-dependent protein kinase binding; protein serine/threonine kinase activity; tau protein binding; INVOLVED IN cellular response to insulin stimulus; intracellular sodium ion homeostasis; long-term memory; PARTICIPATES IN glucocorticoid signaling pathway; insulin signaling pathway; mTOR signaling pathway; ASSOCIATED WITH transient cerebral ischemia; acute myeloid leukemia (ortholog); Animal Mammary Neoplasms (ortholog); FOUND IN perinuclear region of cytoplasm; cytosol (ortholog); nuclear speck (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 11-dehydrocorticosterone; 17alpha-ethynylestradiol

编码一种表现出3-磷酸肌醇依赖性蛋白激酶结合、蛋白丝氨酸/苏氨酸激酶活性、tau蛋白结合的蛋白质；参与细胞对胰岛素刺激的反应、细胞内钠离子稳态、长期记忆；参与糖皮质激素信号通路、胰岛素信号通路、mTOR信号通路；与暂时性脑缺血、急性髓系白血病（同源物）、动物乳腺肿瘤（同源物）相关；存在于细胞质核周区域、细胞溶质（同源物）、核小体（同源物）中；与1,2-二甲基肼、11-脱氢皮质酮、17α-乙炔雌二醇相互作用。