BIOGRID CURATED DATA FOR JKK-1 (Caenorhabditis elegans)

Protein-Protein, Genetic, and Chemical Interactions for JKK-1 (Caenorhabditis elegans) curated by BioGRID (https://thebiogrid.org); DEFINITION: jkk-1 encodes a member of the MAP kinase kinase superfamily that affects synaptic vesicle localization and is required in type-D motor neurons for normal locomotion; can function in the Hog1 MAP kinase pathway I in yeast as an activator of JNK and is expressed in most neurons

蛋白质-蛋白质、遗传以及化学相互作用数据集，针对 Caenorhabditis elegans 中的 JKK-1 基因（由 BioGRID 精心整理，https://thebiogrid.org）；定义：jkk-1 基因编码 MAP 激酶激酶超家族成员，影响突触囊泡定位，并在 D 型运动神经元中对于正常运动行为至关重要；在酵母中，该基因能够作为 Hog1 MAP 激酶通路 I 的激活剂，作用于 JNK，且在大多数神经元中均有表达。