HCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 4c
收藏Protein Data Bank Japan2023-11-01 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3gnw
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资源简介：
HCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 4c Descriptor: (11S)-11-[4-(benzyloxy)-2-fluorophenyl]-3,3-dimethyl-10-[(6-methylpyridin-2-yl)carbonyl]-2,3,4,5,10,11-hexahydrothiopyrano[3,2-b][1,5]benzodiazepin-6-ol 1,1-dioxide, CHLORIDE ION, RNA-directed RNA polymerase Authors: Nyanguile, O, De Bondt, H. Deposit date: 2009-03-18 Release date: 2009-10-20 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.39 Å) Cite: Structure-based design of a benzodiazepine scaffold yields a potent allosteric inhibitor of hepatitis C NS5B RNA polymerase. J.Med.Chem., 52, 2009
创建时间：
2009-03-18
