Genome-wide DNA methylation profiling identifies two novel genes in cervical neoplasia
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE143752
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Using a genome-wide DNA methylation profiling of 186 cervical samples from women with different CIN grades and well-characterized HPV genotyping, we identified novel methylation markers of epigenetic changes that discriminate accurately between clinically significant and transient cervical disease. In particular, a 2-gene DNA methylation classifier (ATP10A and HAS1) showed a promising ability to discriminate among pre-invasive cervical lesion grades. The identified markers are excellent candidates for future diagnostic or prognostic assays in cervical cancer screening. Examination of genome-wide DNA methylation profiling in 186 cervical samples from women with different CIN grades and well-characterized HPV genotyping
创建时间：
2020-01-30
