Data from: Detection of human adaptation during the past 2000 years

Detection of recent natural selection is a challenging problem in
population genetics. Here we introduce the Singleton Density Score (SDS),
a method to infer very recent changes in allele frequencies from
contemporary genome sequences. Applied to data from the UK10K Project, SDS
reflects allele frequency changes in the ancestors of modern Britons
during the past ~2,000-3,000 years. We see strong signals of selection at
lactase and the MHC, and in favor of blond hair and blue eyes. For
polygenic adaptation we find that recent selection for increased height
has driven allele frequency shifts across most of the genome. Moreover, we
identify shifts associated with other complex traits, suggesting that
polygenic adaptation has played a pervasive role in shaping genotypic and
phenotypic variation in modern humans.