Spatial vulnerabilities of the Escherichia coli genome to spontaneous mutations revealed with improved duplex sequencing

Figure S1. Comparison of MAE and MSE strategies. <br>Figure S2. Family size and error rate across all samples. <br>Figure S3. Features of spontaneous mutations.<br>Figure S4. Signatures of mutation context.<br>Figure S5. The spectra and fraction of mutations.<br>Figure S6. The correlation between mutation and gene expression of E3C.<br>Table S1. Summary of data sources for error rate calculation and the 15 E.coli samples sequenced in this study. <br>Table S2. The error rate of the 15 Tp53 duplex sequencing datasets across 12 error types.<br>Table S3. The mutations we obtained in the 15 samples.<br>Table S4 Summary of hotspot across 15 samples.<br>