Crystal structure of aminoglycoside resistance enzyme ApmA, complex with kanamycin B and coenzyme A
收藏Protein Data Bank Japan2026-02-25 更新2026-04-19 收录
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Crystal structure of aminoglycoside resistance enzyme ApmA, complex with kanamycin B and coenzyme A Descriptor: (1R,2S,3S,4R,6S)-4,6-DIAMINO-3-[(3-AMINO-3-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-2-HYDROXYCYCLOHEXYL 2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSIDE, 1,2-ETHANEDIOL, Aminocyclitol acetyltransferase ApmA, ... Authors: Stogios, P.J, Evdokimova, E, Di Leo, R, Bordeleau, E, Wright, G.D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) Deposit date: 2022-04-28 Release date: 2022-11-02 Last modified: 2026-02-25 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Mechanistic plasticity in ApmA enables aminoglycoside promiscuity for resistance Nat.Chem.Biol., 20, 2024
创建时间：
2022-04-28
