five

Crystal structure of the SARS-CoV-2 main protease in complex with 11a

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Protein Data Bank Japan2024-11-13 更新2026-04-25 收录
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Crystal structure of the SARS-CoV-2 main protease in complex with 11a Descriptor: 3C-like proteinase nsp5, methyl (6~{R})-5-ethanoyl-7-oxidanylidene-6-[4-(trifluoromethyl)phenyl]-8,9,10,11-tetrahydro-6~{H}-benzo[b][1,4]benzodiazepine-2-carboxylate Authors: Zeng, R, Liu, Y.Z, Wang, F.L, Yang, S.Y, Lei, J. Deposit date: 2023-06-08 Release date: 2023-08-16 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Discovery of benzodiazepine derivatives as a new class of covalent inhibitors of SARS-CoV-2 main protease. Bioorg.Med.Chem.Lett., 92, 2023
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2023-06-08
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