Xuanfei Baidu Decoction Alleviates Intestinal Inflammation and Modulates Microbiota Distribution by Suppressing several Signaling Pathways

Xuanfei Baidu decoction (XFBD), one of China's recommended prescriptions for COVID-19, has demonstrated clinical efficacy in mitigating virus-induced gastrointestinal inflammation, yet its exact therapeutic mechanism remains incompletely understood, necessitating further in vivo investigation. In this study, we utilized a fruit fly (Drosophila melanogaster) model of intestinal inflammation to assess the therapeutic potential and underlying mechanisms of XFBD.