Fragment Derived XIAP inhibitor
收藏Protein Data Bank Japan2024-05-15 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/6h6r
下载链接
链接失效反馈官方服务：
资源简介：
Fragment Derived XIAP inhibitor Descriptor: 2-[[(2~{R},5~{R})-1-[2-[6-[(4-fluorophenyl)methyl]-3,3-dimethyl-2~{H}-pyrrolo[3,2-b]pyridin-1-yl]-2-oxidanylidene-ethyl]-5-methyl-piperazin-2-yl]methyl]-3~{H}-isoindol-1-one, E3 ubiquitin-protein ligase XIAP, SODIUM ION, ... Authors: Williams, P.A. Deposit date: 2018-07-30 Release date: 2018-08-22 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (2.03 Å) Cite: A Fragment-Derived Clinical Candidate for Antagonism of X-Linked and Cellular Inhibitor of Apoptosis Proteins: 1-(6-[(4-Fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-1 H,2 H,3 H-pyrrolo[3,2- b]pyridin-1-yl)-2-[(2 R,5 R)-5-methyl-2-([(3R)-3-methylmorpholin-4-yl]methyl)piperazin-1-yl]ethan-1-one (ASTX660). J. Med. Chem., 61, 2018
创建时间：
2018-07-30
