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Comparative study of a mTOR inhibitor, a pan-PI3K inhibitor and a dual PI3K/mTOR inhibitor in MCL

ChEBI2013-12-14 更新2026-07-21 收录

靶向药物研发

肿瘤药理学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-53309 数据链接链接失效反馈

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Comparative study of a mTOR inhibitor, a pan-PI3K inhibitor and a dual PI3K/mTOR inhibitor in MCL

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创建时间：

2013-12-14

天然化合物抗肿瘤

肿瘤药理学

Cancer can develop due to abnormal cell proliferation in any body’s cells, so there are over a hundred different types of cancer, each with its distinct behavior and response to treatment. Therefore,

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Main mechanism of action of cisplatin, gemcitabine, vinorelbine and docetaxel.

药物作用机制

肿瘤药理学

Main mechanism of action of cisplatin, gemcitabine, vinorelbine and docetaxel.

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Discovery of Natural Products Targeting NQO1 via an Approach Combining Network-Based Inference and Identification of Privileged Substructures

靶向药物研发

天然药物筛选

NAD(P)H:quinone oxidoreductase 1 (NQO1) has been shown to be a potential therapeutic target for various human diseases, such as cancer and neurodegenerative disorders. Recent advances in computation

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Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST

靶向药物研发

cKIT抑制剂

Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST Descriptor: 5-imidazo[1,2-a]pyridin-3-yl-~{N}-[(1~{R})-1-(6-pyrrolidin-1-ylpyridin-

Protein Data Bank Japan2024-02-07 更新60

Inhibition of A549 cell viability by trypacidin.

肿瘤药理学

毒性评估

A549 cells were exposed for 1 h and 2 h with 10 µM and 50 µM trypacidin, then the medium containing trypacidin was replaced by fresh medium and cell viability was measured 24 h later using MTT assay.

NIAID Data Ecosystem50

Comparative study of a mTOR inhibitor, a pan-PI3K inhibitor and a dual PI3K/mTOR inhibitor in MCL

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