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A Simple Stereocontrolled Synthesis of Salinosporamide A

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/A_Simple_Stereocontrolled_Synthesis_of_Salinosporamide_A/3338359
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A simple and effective stereocontrolled synthesis of salinosporamide A has been developed. This process, the first synthesis of salinosporamide A, is capable of providing the compound in substantial quantities for further biological studies. Salinosporamide A was of special interest as a synthetic target because of its potent in vitro cytotoxic activity against many tumor cell lines (IC50 values of 10 nM or less).
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2016-05-07
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