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Comparison of NAT-lncRNA knockout effect by Next Generation Sequencing

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP405139
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资源简介:
Analysis of different expression of mRNAs and lncRNAs after lncRNA DHRS4-AS1 knockout with two strategies in immortalized human pancreatic duct epithelial cell line HPDE6-C7. The strategies include promoter-exon1(PE) and branch point and 3' splicing site(BESST). The results provide transcriptome comparison between PE and BESST knockout approach, indicating the superior effect of BESST. Overall design: The HPDE-C7 cell line was used in this study, CRISPR-based PE and BESST were applied to knockout DHRS4-RS1 lncRNA. Triplicates were done for each group.
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2023-05-07
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