Data from: Numerical models for assessing the risk of leaflet thrombosis post-transcatheter aortic valve-in-valve implantation

Leaflet thrombosis has been suggested as the reason for the reduced
leaflet motion in cases of hypoattenuated leaflet thickening of
bioprosthetic aortic valves. This work aimed to estimate the risk of
leaflet thrombosis in two post-ViV configurations, using five different
numerical approaches. Realistic ViV configurations were calculated by
modeling the deployments of the latest version of transcatheter aortic
valve devices (Medtronic Evolut PRO, Edwards SAPIEN 3) in the surgical
Sorin Mitroflow. Computational fluid dynamics simulations of blood flow
followed the dry models. Lagrangian and Eulerian measures of near-wall
stagnation were implemented by particle and concentration tracking,
respectively, to estimate the thrombogenicity and to predict the risk
locations. Most of the numerical approaches indicate on a higher leaflet
thrombosis risk in the Edwards SAPIEN 3 device because of its
intra-annular implantation. The Eulerian approaches estimated high-risk
locations in agreement with the WSS separation points. On the other hand,
the Lagrangian approaches predicted high-risk locations at the proximal
regions of the leaflets matching the low WSS magnitude regions of both
TAVI models and reported clinical and experimental data. The proposed
methods can help optimizing future designs of transcatheter aortic valves
with minimal thrombotic risks.