A genome-wide screening identified effector genes of chromatin accessibility. To investigate the functional consequences of the loss of each effector gene, we conducted Mnase-seq with eHAP cells knock
The goal of this study is to investigate how YTHDC1 regulate cardiac development. Overall design: To assess chromatin accessibility in the heart casued by cardiac deletion of Ythdc1, ATAC-seq analysis
The transcription factors Tcf7 (encoding TCF1) and Prdm1 (encoding Blimp1) exhibit opposing effects on T cell differentiation. While TCF1 promotes the maintenance of T progenitor exhausted cells, Blim
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