SK-N-SH cell death after OGD depends on RelA-Lys310 acetylation.

Data show the cell survival of SK-N-SH cells over-expressing a control vector, pSG5, or wild-type RelA or RelA-K310R or RelA-K310Q constructs and exposed to 15 hours of OGD, compared to controls. Wild-type RelA and RelA-K310Q over-expression significantly enhanced toxicity due to OGD, while RelA-K310R over-expression prevented cell loss. Data are mean±s.e.m of three separate experiments run in triplicate and represent the amount of LDH released by each well, relative to total releasable LDH.*p#p