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Additional file 1 of Causal relationship between gut microbiota and tuberculosis: a bidirectional two-sample Mendelian randomization analysis

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Additional file 1: Table S1. STROBE-MR Checklist. Table S2. Excluded single-nucleotide polymorphisms of potential confounders. Table S3. Single-nucleotide polymorphisms used as instrumental variables for TB in the UK Biobank database in MR analysis. Table S4. Single-nucleotide polymorphisms used as instrumental variables for TB in the FinnGen database in MR analysis. Table S5. Full results of MR estimates for the association between gut microbiota and TB in the UK Biobank database. Table S6. Full results of MR estimates for the association between gut microbiota and TB in the FinnGen database. Table S7. Full results of MR estimates for the association between gut microbiota and RTB in the FinnGen database. Table S8. Full results of MR estimates for the association between gut microbiota and EPTB in the FinnGen database. Table S9. Single-nucleotide polymorphisms used as instrumental variables for gut microbiota at the threshold of P < 1e−5 in reverse MR analysis. Table S10. MR results of causal links between TB on gut microbiota at the threshold of P < 1e−5 in the reverse MR analysis. Table S11. Results of MR Steiger direction test. Table S12. Results of sensitivity analyses between gut microbiota and TB with IVW P < 0.05. Table S13. Results of sensitivity analysEs between TB and gut microbiota in the reverse MR analysis.
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