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C2C12 expressing desmin: WT vs Mutations R406W and I451M

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE185589
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C2C12 cell lines were genetically engineered to stably express WT human Desmin or the Desmin mutant R406W or I451M. Non-modified C2C12 cells were used as control. The goal was to determine the effect of different desmin mutation on the gene expression in a myoblast cell line. Three experimental conditions: WT vs control (1 biological sample), R406W vs Control (1 biological sample), I451M vs control (2 biological samples)
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2022-04-06
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