Characterization of parental and erlotinib-resistant derived H1975 cell lines

ChEBI2015-11-19 更新2026-07-12 收录

肿瘤耐药机制

癌细胞系研究

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-74866 数据链接链接失效反馈

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资源简介：

Characterization of parental and erlotinib-resistant derived H1975 cell lines

创建时间：

2015-11-19

Gene expression data from rapamycin resistant and sensitive cell lines

肿瘤耐药机制

miRNA调控

The mammalian target of rapamycin (mTOR) is a central regulator of cell proliferation. Inhibitors of mTOR are being evaluated as anti-tumor agents. Given the emerging role of microRNAs (miRNAs) in tum

NIAID Data Ecosystem70

YAP activation mediates acquired resistance to ALK inhibitor in ALK rearranged non–small cell lung cancer

肿瘤耐药机制

ALK靶向治疗

To investigate a possible candidate for overcoming the acquired resistance to ALK-TKI, we established an in vitro model of acquired resistance to crizotinib (H3122-CR) by exposing EML4-ALK–positive H3

NIAID Data Ecosystem40

Identifying the downstream effectors of E2F7 in squamous cell carcinoma (SCC) cells

肿瘤耐药机制

分子靶点发现

Advanced head and neck squamous cell carcinomas (HNSCC) are frequently drug resistant and have a mortality rate of 40%. We have previously shown that E2F7 may contribute to drug sensitivity. In the pr

NIAID Data Ecosystem30

Suppression of adaptive responses to targeted cancer therapy by transcriptional repression [RNA-seq]. Homo sapiens

肿瘤耐药机制

转录组药物响应

Large-scale genomic profiling efforts have facilitated the characterization of molecular alterations in cancers and aided the development of targeted kinase inhibitors for a wide array of cancer types

NIAID Data Ecosystem50

Comparison of primary neuroblastoma tumors and derivative early-passage cell lines using genome-wide SNP array analysis

神经母细胞瘤基因组学

癌细胞系研究

Comparison of primary neuroblastoma tumors and derivative early-passage cell lines using genome-wide SNP array analysis

ChEBI2009-01-31 更新30